Articles Tagged With:
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Are Beta-Blockers Post-MI Still Necessary?
A large, multicenter, international, randomized clinical trial of long-term beta-blocker therapy vs. no such therapy in contemporary acute myocardial infarction patients who had coronary artery angiography-guided therapy and left ventricular ejection fractions ≥ 50% found no differences in the primary endpoint of all-cause mortality and recurrent myocardial infarction.
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Is Weight Loss the Key to Heart Health?
The second trial of semaglutide in obese patients with heart failure and preserved left ventricular ejection fraction, this one in people with type 2 diabetes, also has shown significant improvements in symptoms and exercise function with significantly fewer adverse effects than placebo-treated patients.
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Transcatheter Myotomy for Left Ventricular Outflow Tract Obstruction
Initial experience with a new transcutaneous transcatheter electrosurgery device using intramyocardial guidewires to create left ventricular upper septum myotomies to enlarge the outflow tract in symptomatic patients with hypertrophic cardiomyopathy, and potentially to enhance transcatheter left heart valve replacement when outflow tract obstruction compromises the procedure, is described in this report from a single center.
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Can Coronary Stenting in Stable Atherosclerotic Coronary Disease Prevent Future Adverse Events?
In this randomized, open-label trial of patients with primarily stable atherosclerotic coronary disease, stenting compared with medical therapy of nonobstructive lesions with imaging markers of plaque vulnerability resulted in a lower incidence of the composite endpoint of cardiac death, target-vessel myocardial infarction, ischemia-driven target vessel revascularization, or hospitalization for unstable or progressive angina at two years.
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Infectious Disease Alert Updates
Nontyphoidal Salmonella Drug Resistance in the United States; Alternative to Fecal Microbiota Transplant; How Best to Save that Prosthetic Joint
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‘Vampire’ Facials and HIV Transmission
Evidence indicates that human immunodeficiency virus was transmitted in association with microneedling of facial lesions with platelet-rich plasma.
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Respiratory Syncytial Virus or Influenza in Older Patients: Which Is Worse?
In individuals 75 years of age or older, respiratory syncytial virus infection was associated with more severe illness than was influenza virus infection.
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Do Bed Nets Prevent Cancer?
When used properly, bed nets prevent malaria in endemic areas. A new systematic review and a meta-analysis confirm that bed net use also is associated with a reduced incidence of Burkitt lymphoma in children in sub-Saharan Africa.
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New (Old) Treatment for Scabies
With increasing concern about reduced effectiveness of topical 5% permethrin cream against scabies, new data show that topical therapy with 25% benzyl benzoate is significantly more effective than permethrin.
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De-Escalation of an Empiric Antipseudomonal Beta-Lactam Is Appropriate with Enterobacterales Bacteremia
Patients with Enterobacterales bacteremia were assigned randomly to receive a course of an anti-pseudomonas beta-lactam or de-escalation to a narrower agent based on sensitivity results. De-escalation was non-inferior to continuing empiric therapy.